The immune system, the body's defense network against infections and injuries, can sometimes become too active. In these ...

An international research team from Bielefeld University and the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has uncovered a previously unknown regulatory mechanism in human cells.

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently ...

Lysosomes are thought of as cellular organelles that play an important role in recycling proteins and maintaning cells by breaking down stuff that isn’t needed. But new research has found that ...

An anticancer treatment technology that selectively targets cancer cell lysosomes and overcomes drug resistance has been developed by Professor Ja-Hyoung Ryu and his research team in the Department of ...

The retromer complex controls protein sorting, transport, and disposal via the endolysosome system. It goes awry in neurodegenerative diseases, but how so remains unclear. Metabolism breaks down in ...

Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer - lysosomal membrane ...

Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular sanitation machines responsible for those tasks, called lysosomes, break ...

The mechanism by which cells detect leaky lysosomes has been revealed, laying the groundwork for new treatments for diseases where lysosomal damage plays a central role. When the cell’s recycling ...

I’d love to read a creepy science fiction story where people dissolve. I asked my friend Anders Omsland if that could happen. He’s a biomedical researcher at Washington State University. He told me a ...