Menopausal Hormone Therapy and Ovarian and Endometrial Cancers: Long-Term Follow-Up of the Women's Health Initiative Randomized Trials Cancers with homologous recombination deficiency (HRD) can ...

Current research has focused on the development of a companion diagnostic to identify sporadic BRCA-like tumors that would allow clinicians to identify those patients who may benefit from drugs ...

DNA double-strand breaks (DSBs) are one of the powerful forces that shape plant genomes. These DSBs may occur throughout the plant life cycle, in somatic or meiotic cells, spontaneously during the ...

Vaccine effectiveness against coronavirus disease 2019 (Covid-19) wanes over time, and boosters are now recommended for residents of the United States starting at the age of 12 years. 1 Clinical ...

Since sister chromatids are identical to each other, recombination with a sister chromatid is expected, in most cases, to be a precise way for repairing DNA damage. Recombination between 2 different ...

The confidence intervals (CI) have not been adjusted for multiplicity, so the intervals should not be used to infer definitive treatment effects for secondary outcomes. The IgG serum binding antibody ...

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly ...

Human chromosomes are constantly assaulted by challenges to their integrity as a result of either environmental agents that damage DNA or from normal DNA metabolism. The failure to repair damaged DNA ...